Why names matter for women: MINOCA/INOCA (myocardial infarction/ischemia and no obstructive coronary artery disease).
Christine Pacheco ClaudioOdayme QuesadaCarl J PepineC Noel Bairey MerzPublished in: Clinical cardiology (2018)
The syndromes of myocardial infarction/myocardial ischemia with No Obstructive Coronary Artery Disease (MINOCA/INOCA) are increasingly evident. A majority of these patients have coronary microvascular dysfunction. These patients have elevated risk for a cardiovascular event (including acute coronary syndrome, myocardial infarction, stroke, and repeated cardiovascular procedures) and appear to be at higher risk for development of heart failure with preserved ejection fraction. Terminology such as coronary artery disease or coronary heart disease is often synonymous with obstructive atherosclerosis in the clinician's mind, leaving one at a loss to recognize or explain the phenomenon of MINOCA and INOCA with elevated risk. We review the available literature regarding stable and unstable ischemic heart disease that suggests that use of the ischemic heart disease (IHD) terminology matters for women, and should facilitate recognition of risk to provide potential treatment targets and optimized health.
Keyphrases
- coronary artery disease
- end stage renal disease
- acute coronary syndrome
- percutaneous coronary intervention
- left ventricular
- ejection fraction
- newly diagnosed
- healthcare
- chronic kidney disease
- peritoneal dialysis
- public health
- prognostic factors
- systematic review
- polycystic ovary syndrome
- mental health
- oxidative stress
- coronary artery
- cardiovascular disease
- risk assessment
- type diabetes
- aortic stenosis
- atrial fibrillation
- blood brain barrier
- combination therapy
- brain injury
- patient reported
- human health
- replacement therapy