Mortality and Complication Rates in Adult Trauma Patients Receiving Tranexamic Acid: A Single-center Experience in the Post-CRASH-2 Era.
Pablo Joaquin ErramouspeMaría Florencia García-PintosSimranjeet BenipalMartin A C ManoukianJohn-Lloyd SantamarinaHiwote G ShawaggaLinda L VoJoseph M GalanteDaniel K NishijimaPublished in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2020)
Adult trauma patients receiving TXA had similar incidences of death but higher incidences of thromboembolic events compared to the CRASH-2 trial. Variation in patient characteristics, injury severity, TXA dosing, and surgery and transfusion rates could explain these observed differences. Further research is necessary to provide additional insight into the incidence and risk factors of thromboembolic events in TXA use.