Central sensitization and severity of gastrointestinal symptoms in irritable bowel syndrome, chronic pain syndromes, and inflammatory bowel disease.

Irina Midenfjord Cecilia GrinsvallPeter KojIda CarnerupHans TörnblomMagnus Simrén

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2021)

Central sensitization was common in IBS and associated with GI symptom severity, but with stronger associations in chronic pain disorders and IBD. This implies that other mechanisms may be of equal or greater importance for GI symptom severity in IBS.

Keyphrases

chronic pain
irritable bowel syndrome
pain management
ulcerative colitis
depressive symptoms
patient reported
physical activity
sleep quality