Inhibition to Epithelial-Mesenchymal Transition and Metastatic Potential In Colorectal Cancer Cell By Combination of Traditional Chinese Medicine Formulation Jiedu Sangen Decoction and PD-L1 Inhibitor.

Feiyu ShanLeitao SunLeyin ZhangKaibo GuoQingying YanGuan FengYing ZhuMinhe ShenShanming Ruan

Published in: Integrative cancer therapies (2021)

These findings indicated that JSAE and a PD-L1 inhibitor could drastically inhibit the migration and invasion of colorectal cancer by reversing EMT through the PI3K/AKT signaling pathway.

Keyphrases

epithelial mesenchymal transition
signaling pathway
transforming growth factor
squamous cell carcinoma
single cell
pi k akt
small cell lung cancer
drug delivery
cell therapy
induced apoptosis
stem cells
climate change
human health
oxidative stress