Multimodal neurometabolic investigation of the effects of zolpidem on leukoencephalopathy-related apathy.

Cécile DelormeI AdanyeguhD BendetowiczI Le BerA PonchelA KasM-O HabertF Mochel

Published in: European journal of neurology (2020)

Our multimodal neurometabolic study suggests that the effects of zolpidem on apathy are related to increased metabolism in the orbitofrontal cortex and basal ganglia secondary to GABA modulation. Zolpidem may improve apathy in other white-matter disorders.

Keyphrases

white matter
pain management
functional connectivity
multiple sclerosis