An observational, multicenter, registry-based cohort study of Turkish Neonatal Society in neonates with Hypoxic ischemic encephalopathy.
Emel OkuluIbrahim Murat HirfanogluMehmet SatarOmer ErdeveEsin KocFerda OzluMahmut GokceDidem ArmangilGaffari TuncNihal DemirelSezin UnalRamazan OzdemirMehmet Fatih DeveciMelek AkarMelike Kefeli DemirelMerih ÇetinkayaHalime Sema Can BukerBelma Saygılı KaragölDeniz YaprakAbdullah Barıs AkcanAyse AnikFatma NarterSema ArayiciEgemen YildirimIlke Mungan AkinOzlem SahinOzgul Emel Bulut OzdemirHusnu Fahri OvalıMustafa Ali AkinYalcin CelikAysen OrmanSinan UsluHilal OzkanNilgun KoksalAyhan TastekinMehmet GunduzAyse Engin ArisoyResat GurpinarRahmi OrsHuseyin AltunhanRamazan KececiHacer Yapicioglu YildizdasDemet TerekMehmet AtesSebnem KaderMehmet MutluKıymet ÇelikEbru YucesoyMustafa Kurthan MertSelvi GulasiKazım KucuktasciDidem ArmanBerna HekimogluNazlı Dilay GultekinHasan Tolga CelikDilek KahveciogluCan AkyildizErdal TaşkınNukhet Aladag CiftdemirSaime Sundus UygunTugba Barsan KayaArzu AkdagAslan YilmazPublished in: PloS one (2023)
The incidence of HIE remained similar over time with a reduction in mortality rate. The timing of TH initiation, whether <3 or 3-6 h, did not result in lower occurrences of brain lesions on MRI or mortality. An increasing number of infants with mild HIE and late preterm infants with HIE are receiving TH; however, the indications for TH require further clarification. Longer follow-up studies are necessary for this vulnerable population.