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Functional inclusion bodies produced in the yeast Pichia pastoris.

Fabián RuedaBrigitte GasserAlejandro Sánchez-ChardiMònica RoldánSandra VillegasVerena PuxbaumNeus Ferrer-MirallesUgutz UnzuetaEsther VázquezElena Garcia-FruitósDiethard MattanovichAntonio Villaverde
Published in: Microbial cell factories (2016)
Structurally and functionally similar from those produced in E. coli, the controlled production of IBs in P. pastoris demonstrates that yeasts can be used as convenient platforms for the biological fabrication of self-organizing protein materials in absence of potential endotoxin contamination and with additional advantages regarding, among others, post-translational modifications often required for protein functionality.
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