Does the ST2 Level in Pediatric Heart Failure Patients Correlate with Cardiovascular Events and Mortality?
Ayse SuluGulcan UnerPelin KosgerBirsen UcarPublished in: Children (Basel, Switzerland) (2024)
In this study, higher sST2 levels were discovered, particularly in the group with valve insufficiency and children with growth retardation. It was associated with the Ross score, but not with the pro BNP level. Although it increases in correlation with clinical heart failure, its predictive value for MACE is low. Similarly, pro BNP is not proven to be predictive; nonetheless, its high levels in patients with hospitalization, growth retardation, lower respiratory tract infection, and organ failure demonstrate that pro BNP may increase for a variety of causes. Long-term studies with more patients are needed for ST2 to be suitable for clinical use in pediatric patients.
Keyphrases
- cardiovascular events
- respiratory tract
- ejection fraction
- heart failure
- coronary artery disease
- anti inflammatory
- end stage renal disease
- cardiovascular disease
- aortic stenosis
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- mitral valve
- type diabetes
- atrial fibrillation
- left ventricular
- patient reported outcomes
- risk factors
- case control
- patient reported