Single intravenous dose ondansetron induces QT prolongation in adult emergency department patients: a prospective observational study.

Mohammad Rezaei Zadeh RukerdFatemeh Rafiei ShahrbabakiMitra MovahediAmin HonarmandPouria PourzandAmirhossein Mirafzal

Published in: International journal of emergency medicine (2024)

Our study demonstrates the predictive capacity of QT0, QTc0, and ondansetron dosage in forecasting QTc60 prolongation (> 480 msec) post-ondansetron administration. These findings advocate for their incorporation into clinical protocols to enhance safety monitoring in adult ED patients.

Keyphrases

emergency department
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
drug induced
low dose
chemotherapy induced