Incidence, clinicopathologic, and genetic characteristics of mismatch repair gene-mutated glioblastomas.

Yoon Ah ChoDeokgeun KimBoram LeeJoon Ho ShimYeon-Lim Suh

Published in: Journal of neuro-oncology (2021)

Since MMR-related genes can be found even in primary glioblastoma and are correlated with high TMB and MGMT promoter methylation, MMR genes should be carefully analyzed in NGS study on glioblastomas.

Keyphrases

genome wide
dna methylation
copy number
genome wide identification
gene expression
risk factors
transcription factor