Comparison of the serum brain-derived neurotrophic factor (BDNF) between fibromyalgia and nociceptive pain groups; and effect of duloxetine on the BDNF level.

Ali Bidari Banafshesh Ghavidel-Parsa Faeze Gharibpoor

Published in: BMC musculoskeletal disorders (2022)

Non-significant BDNF level difference between FM and non-FM nociceptive pain suggested that peripheral BDNF is not a pathophysiological feature of FM. The decreased BDNF level parallel with improvement of PSD/pain scores after duloxetine treatment indicates BDNF alteration in the pain modulation process, regardless of cause and effect.

Keyphrases

neuropathic pain
chronic pain
pain management
stress induced
spinal cord
spinal cord injury
machine learning
deep learning