Higher densities of tumour-infiltrating lymphocytes and CD4+ T cells predict recurrence and progression of ductal carcinoma in situ of the breast.
Aye Aye ThikeXiao-Yang ChenValerie Cui Yun KohNur Diyana Binte Md NasirJoe P S YeongBoon Huat BayPuay Hoon TanPublished in: Histopathology (2021)
DCIS with higher TIL density was associated with poorer prognostic parameters and predicted recurrence, while both CD4+ T cell density and CD4/CD8 ratio were associated with both recurrence and ipsilateral invasive recurrence.
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