Circulating Tumor Cells Characterization Revealed TIMP1 as a Potential Therapeutic Target in Ovarian Cancer.
Manuel AbreuPablo Cabezas-SainzLorena Alonso-AlconadaAlba FerreirósPatricia Mondelo-MacíaRamón Manuel Lago-LestónAlicia AbaloEva DíazSara Palacios-ZambranoAlejandro Rojo-SebastianRafael LópezLaura SánchezGema Moreno-BuenoLaura Muinelo-RomayPublished in: Cells (2020)
Overall, we evidenced the utility of the molecular characterization of EpCAM+ CTCs from advanced ovarian cancer patients to identify biomarkers with potential applicability for disseminated disease detection and as therapeutic targets such as TIMP1.