Login / Signup

7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs.

Jonas Ibn-SalemMiguel A Andrade-Navarro
Published in: BMC genomics (2019)
7C predicts chromatin loops which can help to associate TF binding sites to regulated genes. Furthermore, profiling of hundreds of ChIP-seq datasets results in novel candidate factors functionally involved in chromatin looping. Our method is available as an R/Bioconductor package: http://bioconductor.org/packages/sevenC .
Keyphrases
  • genome wide
  • copy number
  • high throughput
  • single cell
  • dna methylation
  • rna seq
  • circulating tumor cells
  • transcription factor
  • gene expression
  • dna damage
  • molecular dynamics simulations
  • genome wide identification