7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs.
Jonas Ibn-SalemMiguel A Andrade-NavarroPublished in: BMC genomics (2019)
7C predicts chromatin loops which can help to associate TF binding sites to regulated genes. Furthermore, profiling of hundreds of ChIP-seq datasets results in novel candidate factors functionally involved in chromatin looping. Our method is available as an R/Bioconductor package: http://bioconductor.org/packages/sevenC .