Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry.
Brittany D JenkinsRachel N MartiniRupali HireAndrea BrownBriana BennettI'nasia BrownElizabeth W HowerthMary EganJamie HodgsonClayton YatesRick A KittlesDhananjay A ChitaleHaythem Y AliDavid NathansonPetros NikolinakosLisa NewmanMichele MonteilMelissa B DavisPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)
This study has high relevance in cancer management, as we introduce a functional regulator of inflammatory chemokines that can determine an infiltrating tumor immune cell landscape that is distinct among patients of African ancestry.