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Immune gene expression changes more during a malaria transmission season than between consecutive seasons.

Kieran TebbenSalif YirampoDrissa CoulibalyAbdoulaye K KonéMatthew B LaurensEmily M StuckeAhmadou DembéléYoussouf ToloKarim TraoréAmadou NiangalyAndrea A BerryBourèma KouribaChristopher V PloweOgobara K DoumboKirsten E LykeShannon Takala-HarrisonMahamadou A TheraMark A TravassosDavid Serre
Published in: Microbiology spectrum (2024)
malaria changes between infections that occur during low and high malaria transmission seasons, and highlights that immune gene expression changes more during the high transmission season. This provides important insight into the dynamics of the anti-malarial immune response that are important to characterize over these short time frames to better understand how to exploit this immune response with future vaccine efforts.
Keyphrases
  • gene expression
  • plasmodium falciparum
  • immune response
  • dna methylation
  • dendritic cells
  • toll like receptor
  • inflammatory response