Insulin resistance during androgen deprivation therapy in men with prostate cancer.
Shehzad BasariaMary-Ellen TaplinMarie McDonnellDonald C SimonsonAlexander P LinAlyssa B DufourDaniel HabtemariamPaul L NguyenPraful RaviAdam S KibelChristopher J SweeneyAnthony V D'AmicoDaniel A RobertsWenxin XuXiao X WeiRajitha SunkaraAtish D ChoudhuryCharlene MantiaHimisha BeltranMark M PomerantzJacob E BerchuckNeil E MartinJonathan E LeemanKent W MouwKerry E KilbridgeRichelle BearupHannah KackleyHussein KafelGrace HuangKieran F ReidThomas StorerMilena Braga-BasariaThomas G TravisonPublished in: Cancer (2024)
In men with PCa and no diabetes, 24 weeks of ADT did not change insulin resistance despite adverse body composition changes. These findings should be reassuring for treating physicians and for patients who are being considered for short-term ADT.
Keyphrases
- body composition
- insulin resistance
- prostate cancer
- type diabetes
- end stage renal disease
- adipose tissue
- metabolic syndrome
- newly diagnosed
- resistance training
- ejection fraction
- high fat diet
- bone mineral density
- primary care
- chronic kidney disease
- cardiovascular disease
- polycystic ovary syndrome
- middle aged
- glycemic control
- radical prostatectomy
- skeletal muscle
- peritoneal dialysis
- stem cells
- high fat diet induced
- emergency department
- patient reported outcomes
- postmenopausal women