Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats.

Elizabeth Enohnyket BesongTunmise Maryanne AkhigbePrecious Jesutofunmi AshonibareAbimbola Ayoola OladipoJacinta Nkechi ObimmaMoses Agbomhere HamedDamilare Hakeem AdeyemiRoland Eghoghosoa Akhigbe

Published in: Redox report : communications in free radical research (2023)

This study revealed that co-administration of zinc improves lead-induced sexual and erectile dysfunction by suppressing XO/UA-driven oxidative stress and upregulating testosterone via Nrf2-mediated signaling.

Keyphrases

oxidative stress
diabetic rats
replacement therapy
mental health
oxide nanoparticles
high glucose
dna damage
ischemia reperfusion injury
single cell
induced apoptosis
smoking cessation
stress induced
endothelial cells