Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Chronic Ethanol-Induced Cardiac Fibrosis by Restoring Autophagic Flux.

Chi ZhouJin HuangQing LiChenao ZhanYing HeJinyan LiuZheng WenDao Wen Wang

Published in: Alcoholism, clinical and experimental research (2018)

Taken together, these findings suggest that sEH pharmacological inhibition may be a unique therapeutic strategy for treating EtOH-induced cardiac fibrosis.

Keyphrases

high glucose
diabetic rats
left ventricular
drug induced
cell death
endothelial cells
heart failure
oxidative stress
liver fibrosis