Maternal choline supplementation in a rat model of periconceptional alcohol exposure: Impacts on the fetus and placenta.

Sarah E SteaneArree M FieldingNykola L KentIsabella AndersenDaniel J BrowneEllen N TejoEmelie M GårdebjerJacinta I Kalisch-SmithMitchell A SullivanKaren M MoritzLisa K Akison

Published in: Alcoholism, clinical and experimental research (2021)

Our results suggest that choline has the potential to ameliorate fetal growth restriction associated with PCE and improve placental efficiency following prenatal alcohol exposure. Our study highlights the importance of maternal nutrition in moderating the severity of adverse fetal and placental outcomes that may arise from prenatal alcohol exposure around the time of conception.

Keyphrases

pregnant women
alcohol consumption
pregnancy outcomes
physical activity
type diabetes
metabolic syndrome
weight loss
human health
gestational age