Development of ventricular trabeculae affects electrical conduction in the early endothermic heart.
Veronika OlejnickovaPeter Uriel HamorJiří JanáčekMartin BartosEva ZabrodskaBarbora SankovaAlena KvasilovaHana KolesováDavid SedmeraPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2022)
Our results showed the essential role of trabeculae in intraventricular impulse spreading and conduction patterning in the early endothermic heart. Lack of trabeculae leads to the failure of conduction parameters differentiation resulting in primitive ventricular activation with consequent impact on the cardiac pumping function.