Epigenetic regulation of inflammation by microRNAs in post-infectious bronchiolitis obliterans.
Ruth Pia DueckerInes De Mir MessaSilvija-Pera JerkicAnnalena KochemsGabriele GottwaldAntonio Moreno-GaldóMartin RosewichLucia GronauStefan ZielenAndreas Geburtig-ChiocchettiHermann KreyenbergRalf SchubertPublished in: Clinical & translational immunology (2022)
Our results demonstrate an aberrant miRNA expression profile in PiBO, which impacts pathways responsible for the regulation of inflammation and fibrosis. The defined miRNAs are useful biomarkers and should be assessed as potential target in the field of miRNA therapeutics.