Temporal dynamics and drivers of durable HIV viral load suppression and persistent high- and low-level viremia during Universal Test and Treat scale-up in Uganda: a population-based study.
Joseph Gregory RosenRobert SsekubuguLarry W ChangVictor SsempijjaRonald M GaliwangoJoseph SsekasanvuAnthony NdyanaboAlice KisakyeGertrude NakigoziKatherine B RucinskiEshan U PatelCaitlin E KennedyFred NalugodaGodfrey KigoziOliver RatmannLisa J NelsonLisa A MillsDonna KabatesiAaron A R TobianThomas C QuinnJoseph KagaayiSteven J ReynoldsM Kate GrabowskiPublished in: medRxiv : the preprint server for health sciences (2023)
Following universal ART provision, most persons living with HIV in south-central Uganda are durably suppressed. Among persons exhibiting viremia, nearly half maintain high-level viremia for ≥12 months and report higher-risk behaviors associated with onward HIV transmission. Enhanced linkage to HIV care and optimized treatment retention could accelerate momentum towards HIV epidemic control.