Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia.
Ana Rosa CidPau MontesinosIsabel Sánchez-GuiuSaturnino HayaJose I LorenzoJaime SanzFederico MoscardoNieves PuigDolores PlanellesSantiago BonanadGuillermo F SanzVicente VicenteConsuelo González-ManchónMaría L LozanoJosé RiveraMiguel A SanzPublished in: Clinical case reports (2017)
Glanzmann thrombasthenia is a rare bleeding disorder that can present life-threatening bleeding. Our patients develop antiplatelet antibodies that become refractory to any pharmacological treatment. Allogeneic hematopoietic stem-cell transplantation is the only currently curative procedure, but has major risks mainly in adult; indeed, our patient died.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- case report
- prognostic factors
- atrial fibrillation
- newly diagnosed
- ejection fraction
- acute myeloid leukemia
- acute lymphoblastic leukemia
- stem cell transplantation
- chronic kidney disease
- peritoneal dialysis
- bone marrow
- minimally invasive
- rectal cancer
- young adults
- combination therapy
- low dose
- hematopoietic stem cell
- climate change
- patient reported