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RNA binding protein HuD promotes autophagy and tumor stress survival by suppressing mTORC1 activity and augmenting ARL6IP1 levels.

Kausik BishayeeKhadija HabibUddin Md NazimJieun KangAniko SzaboSung-Oh HuhAli Sadra
Published in: Journal of experimental & clinical cancer research : CR (2022)
HuD is seen as a novel means of promoting stress survival in this cancer type by downregulating mTORC1 activity and negatively regulating apoptosis.
Keyphrases
  • binding protein
  • endoplasmic reticulum stress
  • oxidative stress
  • cell death
  • papillary thyroid
  • free survival
  • signaling pathway
  • squamous cell carcinoma
  • squamous cell
  • pi k akt