Neurocognitive effect of biased µ-opioid receptor agonist oliceridine, a utility function analysis and comparison with morphine.
Laurence MossHemme HijmaMark DemitrackJessica KimGeert Jan GroeneveldMonique van VelzenMarieke NiestersErik OlofsenAlbert DahanPublished in: Anesthesiology (2023)
These data indicate that over the clinical concentration range, oliceridine is an analgesic with a favorable safety profile over morphine when considering analgesia and neurocognitive function.