Phosphoproteomics Reveals the Wolframin-Calcium Axis as an Important Pathogenic Signaling Node in Primary Aldosteronism.

Linqiang MaShumin YangYi YangXiangjun ChenJun YangYifan HeQingfeng ChengJunlong LiBing KangSiying TangAipin ZhangXiaoyu ShuXiaoyu LiShumin YangYing JingYing SongQi Fu Li Jinbo Hu

Published in: Hypertension (Dallas, Tex. : 1979) (2023)

Wolframin is a regulatory protein in aldosterone hypersecretion. Remodeled calcium transportation and mitochondrial function are involved in wolframin-related aldosterone secretion.

Keyphrases

angiotensin ii
lymph node
transcription factor
binding protein
small molecule