Secreted Frizzled-Related Protein 2 and Extracellular Volume Fraction in Patients with Heart Failure.
Shaomin YangHaixiong ChenKuan TanFusheng CaiYongxing DuWei-Biao LvQiugen HuYunzhao HuYuli HuangPublished in: Oxidative medicine and cellular longevity (2020)
Higher ECV fraction is associated with worsened prognosis in HF. SFRP2 is an independent biomarker for myocardial fibrosis. Further studies are needed to explore the potential therapeutic value of SFRP2 in myocardial fibrosis.