Composite Plot for Visualizing Aminotransferase and Bilirubin Changes in Clinical Trials of Subjects with Abnormal Baseline Values.
Bereket TesfaldetTejas PatelMinjun ChenFrank PucinoLilliam RosarioPaul HayashiEileen Navarro AlmarioPublished in: Drug safety (2024)
For studies in subjects with abnormal baseline values, the composite plot has potential application in the assessment of beneficial and concerning on-treatment modifications in liver test values in reference to the individual subject's baseline and population threshold values.