Evidence for a causal association between milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals.
Karani Santhanakrishnan VimaleswaranAng ZhouAlana CavadinoElina HyppӧnenPublished in: International journal of obesity (2005) (2021)
Our large-scale MR study provides genetic evidence for the association of milk consumption with higher BMI but lower serum cholesterol levels. These data suggest no need to limit milk intakes with respect to cardiovascular disease risk, with the suggested benefits requiring confirmation in further studies.
Keyphrases
- cardiovascular disease
- body mass index
- type diabetes
- weight gain
- magnetic resonance
- electronic health record
- big data
- genome wide
- metabolic syndrome
- coronary artery disease
- cardiovascular events
- contrast enhanced
- gene expression
- dna methylation
- physical activity
- artificial intelligence
- insulin resistance
- data analysis