Analytical and Clinical Performance of Droplet Digital PCR in the Detection and Quantification of SARS-CoV-2.

Kyoung-Bo Kim Hayoung ChoiGun Dong LeeJaewoong Lee Seungok Lee Yonggoo Kim Sung-Yeon Cho Dong-Gun Lee Myung-Shin Kim

Published in: Molecular diagnosis & therapy (2021)

Droplet digital polymerase chain reaction demonstrated excellent sensitivity for SARS-Cov-2 detection and consistently agreed with the results from conventional RT-qPCR. Furthermore, ddPCR provided quantitative data that can be used to monitor changes in the viral load of patients with COVID-19.

Keyphrases

sars cov
real time pcr
respiratory syndrome coronavirus
loop mediated isothermal amplification
single cell
high throughput
label free
electronic health record
high resolution
machine learning
mass spectrometry
coronavirus disease