Intestinal P-glycoprotein inhibitors, benzoxanthone analogues.

Song Wha ChaeJaeok LeeJung Hyun ParkYoungjoo KwonYounghwa NaHwa Jeong Lee

Published in: The Journal of pharmacy and pharmacology (2017)

Benzoxanthone analogue, compound 1 is strongly suggested to be a promising inhibitor of P-gp to improve an oral absorption of compounds for cancer therapy.

Keyphrases

cancer therapy
drug delivery
molecular docking
structure activity relationship
molecular dynamics simulations