High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype.

Yoichi KakutaYasuhiro IzumiyamaDaisuke OkamotoTakeru NakanoRyo IchikawaTakeo NaitoRintaro MoroiMasatake KurohaYoshitake KanazawaTomoya KimuraHisashi ShigaHisaaki KudoNaoko MinegishiYosuke KawaiKatsushi TokunagaMasao NagasakiYoshitaka KinouchiYasuo SuzukiAtsushi Masasmunenull null

Published in: Journal of gastroenterology (2019)

Our study showed that HRM method enables simple genotyping of complicated codon 18 variants essential to haplotype estimation of the NUDT15.

Keyphrases

high resolution
genome wide
high throughput
copy number
mass spectrometry
genetic diversity
single cell
data analysis