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High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype.

Yoichi KakutaYasuhiro IzumiyamaDaisuke OkamotoTakeru NakanoRyo IchikawaTakeo NaitoRintaro MoroiMasatake KurohaYoshitake KanazawaTomoya KimuraHisashi ShigaHisaaki KudoNaoko MinegishiYosuke KawaiKatsushi TokunagaMasao NagasakiYoshitaka KinouchiYasuo SuzukiAtsushi Masasmunenull null
Published in: Journal of gastroenterology (2019)
Our study showed that HRM method enables simple genotyping of complicated codon 18 variants essential to haplotype estimation of the NUDT15.
Keyphrases
  • high resolution
  • genome wide
  • high throughput
  • copy number
  • mass spectrometry
  • genetic diversity
  • single cell
  • data analysis