Morpho-Functional Changes of Nigral Dopamine Neurons in an α-Synuclein Model of Parkinson's Disease.

Ada LedonneMariangela Massaro CenereEmanuela PaldinoVincenza D'AngeloSebastian Luca D'Addario Nicolas Casadei Annalisa NobiliNicola BerrettaFrancesca R FuscoRossella VenturaGiuseppe Sancesario Ezia Guatteo Nicola Biagio Mercuri

Published in: Movement disorders : official journal of the Movement Disorder Society (2022)

Besides clarifying α-syn-induced pathological landmarks, such evidence reveals compensatory functional mechanisms that nigral DA neurons could adopt during PD progression to counteract neurodegeneration. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

spinal cord
high glucose
diabetic rats
uric acid
drug induced
oxidative stress
metabolic syndrome