Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Study†.
Tafadzwa MachipisaChishala ChishalaGasnat ShaboodienLiesl J ZühlkeBabu MuhamedShahiemah PandieJantina de VriesNakita LaingAlexia JoachimRezeen DanielsMpiko NtsekheChristopher T Hugo-HammanBernard GituraStephen OgendoPeter S LwabiEmmy OkelloAlbertino DamascenoCelia NovelaAna Olga MocumbiGeoffrey MadeiraJohn MusukuAgnes MtajaAhmed ElSayedHuda H M AlhassanFidelia Bode-ThomasChristopher S YilgwanGaniyu AmusaEsin NkereuwemNicola MulderRajkumar RamesarMaia LesoskyHeather J CordellMichael ChongBernard D KeavneyGuillaume ParéMark M Engelnull nullPublished in: Circulation. Genomic and precision medicine (2022)
RHDGen presents a rare opportunity to identify relevant patterns of genetic factors and biomarkers in Africans that may be associated with differential RHD risk. Furthermore, the RHDGen Network provides a platform for further work on fully elucidating the causes and mechanisms associated with RHD susceptibility and development.