Rescue of p53 functions by in vitro-transcribed mRNA impedes the growth of high-grade serous ovarian cancer.

Monika RaabIzabela KostovaSamuel Peña-LlopisDaniela FietzMonika KressinSeyed Mohsen AberoumandiEvelyn UllrichSven BeckerMourad SanhajiKlaus Strebhardt

Published in: Cancer communications (London, England) (2023)

The IVT mRNA-based reactivation of p53 holds promise as a potential therapeutic strategy for HGSOC, providing valuable insights into the molecular mechanisms underlying p53 function and its relevance in ovarian cancer treatment.

Keyphrases

high grade
low grade
binding protein
big data
single molecule
artificial intelligence
deep learning