Genetic Implication of Prenatal GABAergic and Cholinergic Neuron Development in Susceptibility to Schizophrenia.

Darren CameronNgoc-Nga VinhParinda PrapaiwongsElizabeth A PerryJames T R WaltersMeng LiMichael C O'DonovanNicholas J Bray

Published in: Schizophrenia bulletin (2024)

Our study implicates prenatal development of specific populations of GABAergic and cholinergic neurons in later susceptibility to schizophrenia, and provides a map of predicted regulatory genomic elements operating in cells of the GE.

Keyphrases

bipolar disorder
pregnant women
induced apoptosis
copy number
cell cycle arrest
signaling pathway
oxidative stress
cell proliferation