Relationship between rs4349859 and rs116488202 polymorphisms close to MHC-I region and serum urate levels in patients with gout.
Javier Fernández-TorresYessica Zamudio-CuevasGabriela Angélica Martínez-NavaKarina Martínez FloresXiadani Ruíz-DávilaRoberto Sánchez-SánchezPublished in: Molecular biology reports (2023)
The study revealed that rs4349859 and rs116488202 SNPs close to MHC-I region confers strong susceptibility to gout in Mexican population, and the heterozygous genotypes of both were associated with higher levels of SU.