Relationship between rs4349859 and rs116488202 polymorphisms close to MHC-I region and serum urate levels in patients with gout.

Javier Fernández-Torres Yessica Zamudio-Cuevas Gabriela Angélica Martínez-Nava Karina Martínez FloresXiadani Ruíz-DávilaRoberto Sánchez-Sánchez

Published in: Molecular biology reports (2023)

The study revealed that rs4349859 and rs116488202 SNPs close to MHC-I region confers strong susceptibility to gout in Mexican population, and the heterozygous genotypes of both were associated with higher levels of SU.

Keyphrases

uric acid
early onset
genome wide
metabolic syndrome
dna methylation