Activation-induced pyroptosis contributes to the loss of MAIT cells in chronic HIV-1 infected patients.

Peng XiaXu-Dong XingCui-Xian YangXue-Jiao LiaoFu-Hua LiuHui-Huang HuangChao ZhangJin-Wen SongYan-Mei JiaoMing ShiTian-Jun JiangChun-Bao ZhouXi-Cheng WangQing HeQing-Lei ZengFu-Sheng WangJi-Yuan Zhang

Published in: Military Medical Research (2022)

Activation-induced MAIT cell pyroptosis contributes to the loss of MAIT cells in HIV-1 infected patients, which could potentiate disease progression and poor immune reconstitution.

Keyphrases

hiv infected patients
antiretroviral therapy
induced apoptosis
cell cycle arrest
high glucose
diabetic rats
drug induced
nlrp inflammasome
oxidative stress
stem cells
single cell
cell therapy
mesenchymal stem cells
endothelial cells