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T2-FLAIR Mismatch Sign Predicts DNA Methylation Subclass and CDKN2A/B Status in IDH-Mutant Astrocytomas.

Matthew D LeeRajan JainKristyn GalbraithAnna ChenEvan LiebermanSohil H PatelDimitris G PlacantonakisDavid ZagzagMarissa BarbaroMaria Del Pilar Guillermo Prieto EiblJohn G GolfinosDaniel A OrringerMatija Snuderl
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
The T2-FLAIR mismatch sign is highly specific for low methylation grade and intact CDKN2A/B in IDH-mutant astrocytomas.
Keyphrases
  • wild type
  • dna methylation
  • genome wide
  • low grade
  • gene expression
  • copy number
  • high grade