Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy.

Meiying LiFei MaJiayu WangQing LiPin ZhangPeng YuanYang LuoRuigang CaiYing FanShanshan ChenQiao LiBinghe Xu

Published in: Chinese journal of cancer (2018)

ATG5 rs473543 genotypes may serve as a potential marker for predicting recurrence of early-stage TNBC patients who received anthracycline-and/or taxane-based regimens as adjuvant chemotherapy.

Keyphrases

early stage
metastatic breast cancer
cell death
endoplasmic reticulum stress
genome wide
signaling pathway
oxidative stress
copy number
squamous cell carcinoma
human health
gene expression
risk assessment
dna methylation
lymph node
rectal cancer
neoadjuvant chemotherapy