Excess Weight, Polygenic Risk Score, and Findings of Colorectal Neoplasms at Screening Colonoscopy.

Ruojin FuXuechen Chen Tobias Niedermaier Teresa L Seum Michael Hoffmeister Hermann Brenner

Published in: The American journal of gastroenterology (2024)

Excess weight and polygenic risk are associated with increased risk of colorectal neoplasms in a multiplicative manner. Maintaining normal weight is estimated to have an equivalent effect as having 38 percentiles lower PRS.

Keyphrases

body mass index
weight loss
physical activity
weight gain
body weight