GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli.
Xiaowei WangQinggang LiCunmin SunZhen CaiXiaomei ZhengXuan GuoXiaomeng NiWenjuan ZhouYanmei GuoPing ZhengNing ChenJibin SunYin LiYanhe MaPublished in: Microbial cell factories (2019)
Our present study indicates that improving a lysine hyperproducer by GREACE-assisted ALE in its stressful living environment is efficient and effective. Accordingly, this is a promising method for improving other valuable chemical hyperproducers.
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