Massive iron overload and acute-on-chronic liver failure in a patient with Diamond-Blackfan anaemia: a case report.
Guilherme Rossi Assis de MendonçaMarlone Cunha-SilvaMariana Franson FernandesLuiza Dias TorresMonica Pinheiro de Almeida VerissimoMarcelo Trevisan Neves OkanoDaniel Ferraz MazoCristina Alba LalliTiago Sevá-PereiraRafael Fantelli SteliniLarissa Bastos Eloy da CostaPublished in: BMC gastroenterology (2020)
This is the first case reporting the sequence: DBA, multiple blood transfusions, secondary haemochromatosis, advanced liver fibrosis, heart failure, ACLF and death. A multidisciplinary team is essential to care for DBA patients, since there is a significant emotional burden related to the disease, which might impair an effective chelation therapy and lead to severe consequences due to iron deposition.
Keyphrases
- liver failure
- liver fibrosis
- heart failure
- hepatitis b virus
- end stage renal disease
- palliative care
- quality improvement
- iron deficiency
- ejection fraction
- drug induced
- healthcare
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- left ventricular
- prognostic factors
- case report
- emergency department
- early onset
- mesenchymal stem cells
- pain management
- mechanical ventilation
- smoking cessation