Plasma neurofilament light chain predicts Alzheimer's disease in patients with subjective cognitive decline and mild cognitive impairment: A cross-sectional and longitudinal study.
Salvatore MazzeoAssunta IngannatoGiulia GiacomucciAlberto ManganelliValentina MoschiniJuri BalestriniArianna CavaliereCarmen MorinelliGiulia GaldoFilippo EmilianiDiletta PiazzesiChiara CrucittiDaniele FrigerioCristina PolitoValentina BertiSilvia BagnoliSonia PadiglioniSandro SorbiBenedetta NacmiasValentina BessiPublished in: European journal of neurology (2023)
Plasma NfL concentration and change over time may be a reliable, non-invasive tool to detect AD and the progression of cognitive decline at the earliest stages of the disease.