Beyond ISN/RPS Lupus Nephritis Classification: Adding Chronicity Index to Clinical Variables Predicts Kidney Survival.

Gabriella Moroni Giulia PorataFrancesca RaffiottaSilvana QuagliniGiulia FrontiniLucia SacchiValentina BindaMarta CalatroniFrancesco ReggianiGiovanni BanfiClaudio Ponticelli

Published in: Kidney360 (2021)

The chronicity index and its components, but not the activity index, were significantly associated with an impairment of kidney function. The Cox model showed that serum creatinine, arterial hypertension, chronic glomerular lesions, and delay in kidney biopsy predicted KFI. These data reinforce the importance of timely kidney biopsy in LN.

Keyphrases

arterial hypertension
ultrasound guided
fine needle aspiration
machine learning
deep learning
electronic health record
uric acid
drug induced
data analysis
diabetic nephropathy
endothelial cells
high glucose