Effects of platelet-rich plasma on the memory impairment, apoptosis, and hippocampal synaptic plasticity in a rat model of hepatic encephalopathy.

Mahnaz BayatAzadeh KhaliliGholamreza BayatSomayeh AkbariAmirhossein Yousefi NejadAfshin Borhani HaghighiMahnaz Bayat

Published in: Brain and behavior (2021)

The results of this study suggest that PRP improves cognitive performance and synaptic plasticity in BDL rats via direct neuroprotective property and/or indirectly by improvement of hepatic dysfunction.

Keyphrases

platelet rich plasma
oxidative stress
cerebral ischemia
endoplasmic reticulum stress
cell death
working memory
early onset
cell cycle arrest
cell proliferation
blood brain barrier