Association of maternal risk factors with the recent rise of neural tube defects in Canada.
Shiliang LiuJane EvansAmanda J MacFarlaneCande V AnanthJulian LittleMichael S KramerK S JosephPublished in: Paediatric and perinatal epidemiology (2019)
Increases in the frequency of maternal risk factors such as pregestational diabetes mellitus, substance use, and chronic illness may be partly responsible for the recent rise in NTDs, particularly spina bifida.