Prevalence of Enteric Infections in Patients on Immune Checkpoint Inhibitors and Impact on Management and Outcomes.
Patrick Tiongco MagahisDeepika SatishNgolela Esther BabadyMini KambojMichael A PostowMonika LaszkowskaDavid M FaleckPublished in: The oncologist (2023)
GI infections in ICI-treated patients presenting with diarrhea are linked to more severe but self-limited clinical presentations and may be optimally treated with observation and supportive care alone. Routine and timely stool pathogen testing may help avert unnecessary empiric immunosuppression for suspected irEC, which has been linked to blunted antitumor responses and numerous adverse effects.
Keyphrases
- newly diagnosed
- end stage renal disease
- ejection fraction
- healthcare
- chronic kidney disease
- palliative care
- prognostic factors
- peritoneal dialysis
- early onset
- type diabetes
- patient reported outcomes
- metabolic syndrome
- clinical practice
- pain management
- candida albicans
- skeletal muscle
- affordable care act
- chronic pain
- drug induced
- irritable bowel syndrome