Urinary desmosine is associated with emphysema severity and frequent exacerbation in patients with COPD.

Changhwan KimYousang KoSu Hee KimHyun Ju YooJae Seung LeeChin Kook RheeJin Hwa LeeJi-Hyun LeeTae-Hyung KimSeong Yong LimKwang Ha YooJoon Beom SeoYeon-Mok OhSang-Do LeeYong Bum Park

Published in: Respirology (Carlton, Vic.) (2017)

This study indicates that the level of urinary desmosines measured by LC-MS/MS methods is associated with the CT emphysema index. Urinary desmosine can be a useful predictor in identifying frequent exacerbators.

Keyphrases

chronic obstructive pulmonary disease
lung function
computed tomography
idiopathic pulmonary fibrosis
pulmonary fibrosis
image quality
cystic fibrosis
positron emission tomography
dual energy
intensive care unit
magnetic resonance
mechanical ventilation
extracorporeal membrane oxygenation
respiratory failure